Pistorius Case: Agent Cancels All Future Races












Oscar Pistorius won't run in any of the future races that the athlete was contracted to compete in, but the Paraylmpic gold medalist's sponsors are still supportive as he faces a murder charge, his agent said today.


The decision to cancel Pistorius' scheduled appearances was made to "allow Oscar to concentrate on the upcoming legal proceedings and to help and support all those involved as they try to come to terms with this very difficult and distressing situation," Peet Van Zyl of In Site Athlete Management said in a statement.


"I have decided that following these tragic events that we have no option but to cancel all future races that Oscar Pistorius had been contracted to compete in," Van Zyl said.


Pistorius was slated to compete in races in Australia and Brazil, as well as at the Drake Relays in Iowa and the Manchester City Games in the U.K.


Van Zyl also said that Pistorius' sponsors and partners are supportive.


"I can confirm that at this point in time, all parties are supportive and their contractual commitments are maintained. They have said they are happy to let the legal process takes its course before making any change in their position," Van Zyl said in the statement.


However, M-Net movies, a subscription-funded South African television channel has pulled their ad campaign featuring Pistorius, tweeting, "Out of respect & sympathy to the bereaved, M-Net will be pulling its entire Oscar campaign featuring Oscar Pistorius with immediate effect."


The agent's announcement comes as family and friends rallied to Pistorius' defense -- saying they believe the Paralympic gold medalist's story that he shot his model girlfriend Reeva Steenkamp by accident after he mistook her for an intruder.






Adrian Dennis/AFP/Getty Images; Mike Holmes/The Herald/Gallo Images/Getty Images











'Blade Runner' Murder Mystery: Family Speaks Out Watch Video









'Blade Runner' on Suicide Watch After Charged With Girlfriend's Murder Watch Video









Oscar Pistorius Charged in Shooting Death of Girlfriend Watch Video





"When you are a sportsman, you act even more on instinct ... it's instinct -- things happen and that's what you do," Pistorius' father Henke Pistorius, 59, told The Telegraph.


The 26-year-old athlete, known as the "Blade Runner" because of the carbon-fiber blades he runs on, was charged Friday with premeditated murder.


PHOTOS: Paralympic Champion Charged With Murder


If convicted, Pistorius could face at least 25 years in jail.


"All of us saw at firsthand how close [Steenkamp] had become to Oscar during that time and how happy they were. They had plans together and Oscar was happier in his private life than he had been for a long time," Pistorius' uncle Arnold Pistorius said on Saturday.


According to South African newspaper Beeld, Steenkamp was killed nearly two hours after police were called to Pistorius' home to respond to reports of an argument at the complex.


Police said they have responded to disputes at the sprinter's residence before, but did not say whether Steenkamp was involved.


The athlete's best friend said Pistorius called him after the shooting to say "there has been a terrible accident, I shot Reeva," Justin Divaris told the Sunday People.


While his family insists he is not a murderer, prosecutors disagree.


Police sources told local media that Steenkamp was shot through the bathroom door where she may have been trying to hide to save herself.


Reeva Steenkamp


A memorial service for Steenkamp will be held in Port Elizabeth on Tuesday evening, SABC reported. Her body will be flown back for the service before being cremated, her family said.


"Her future has been cut short ... I dare say she's with the angels," said Mike Steenkamp, Reeva Steenkamp's uncle.


The South African reality show Steenkamp competed in premiered Saturday night on SABC as planned and included a special tribute to the slain law school graduate whose modeling career was starting to take off.






Read More..

False memories prime immune system for future attacks









































IN A police line-up, a falsely remembered face is a big problem. But for the body's police force – the immune system – false memories could be a crucial weapon.












When a new bacterium or virus invades the body, the immune system mounts an attack by sending in white blood cells called T-cells that are tailored to the molecular structure of that invader. Defeating the infection can take several weeks. However, once victorious, some T-cells stick around, turning into memory cells that remember the invader, reducing the time taken to kill it the next time it turns up.












Conventional thinking has it that memory cells for a particular microbe only form in response to an infection. "The dogma is that you need to be exposed," says Mark Davis of Stanford University in California, but now he and his colleagues have shown that this is not always the case.












The team took 26 samples from the Stanford Blood Center. All 26 people had been screened for diseases and had never been infected with HIV, herpes simplex virus or cytomegalovirus. Despite this, Davis's team found that all the samples contained T-cells tailored to these viruses, and an average of 50 per cent of these cells were memory cells.












The idea that T-cells don't need to be exposed to the pathogen "is paradigm shifting," says Philip Ashton-Rickardt of Imperial College London, who was not involved in the study. "Not only do they have capacity to remember, they seem to have seen a virus when they haven't."












So how are these false memories created? To a T-cell, each virus is "just a collection of peptides", says Davis. And so different microbes could have structures that are similar enough to confuse the T-cells.












To test this idea, the researchers vaccinated two people with an H1N1 strain of influenza and found that this also stimulated the T-cells to react to two bacteria with a similar peptide structure. Exposing the samples from the blood bank to peptide sequences from certain gut and soil bacteria and a species of ocean algae resulted in an immune response to HIV (Immunology, doi.org/kgg).












The finding could explain why vaccinating children against measles seems to improve mortality rates from other diseases. It also raises the possibility of creating a database of cross-reactive microbes to find new vaccination strategies. "We need to start exploring case by case," says Davis.












"You could find innocuous pathogens that are good at vaccinating against nasty ones," says Ashton-Rickardt. The idea of cross-reactivity is as old as immunology, he says. But he is excited about the potential for finding unexpected correlations. "Who could have predicted that HIV was related to an ocean algae?" he says. "No one's going to make that up!"












This article appeared in print under the headline "False memories prime our defences"




















































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Aviation industry dons 'shark skins' to save fuel






FRANKFURT: In its never-ending quest to develop more aerodynamic, more fuel-efficient aircraft, the aviation industry believes the ocean's oldest predator, the shark, could hold the key to cutting energy consumption.

Germany's biggest airline Lufthansa announced earlier this month that two of its Airbus A340-300 jets would take part in trials starting this summer to test the properties of shark skin in flight.

For the two-year trials, eight 10 by 10 centimetre (4 by 4 inch) patches of a new type of coating are being painted on to the fuselage and wing edges of the aircraft.

A new state-of-the-art varnish, developed by the Fraunhofer Institute for Manufacturing Technology and Advanced Materials (FAM) in Bremen, attempts to mimic the skins of fast-swimming sharks.

The skin of sharks is covered in tiny riblets that reduce turbulent vortices and the drag they cause, thereby diminishing surface resistance when moving at speed.

The phenomenon of the streamlined shark skin has been known for about 30 years and has fascinated research scientists in a wide range of fields, from military applications to aerospace and aeronautics and from naval construction to wind technology.

More recently, its use in sports such as swimming and athletics has brought the special properties of shark skin to much wider attention.

High-tech swimsuits were developed that enabled athletes to move ever faster through water, breaking one swimming record after the next until the suits were eventually banned as unfair in competition.

In the past, says Volkmar Stenzel, the project's head at the Fraunhofer Institute, sheets of plastic imitation shark skin were glued to the aircraft's exterior.

"But the foil had major disadvantages: it was rather heavy and the added weight cancelled out the amount of fuel that could be saved," Stenzel said.

"Also, it was difficult to stick the foil to curved surfaces without creasing and wrinkling," he said.

Another problem was that aircraft have to be stripped of their paint and recoated every five years "and that was just not possible with these foils," the expert explained.

Thus, in collaboration with European aircraft maker Airbus and the DLR German Aerospace Center, scientists at the Fraunhofer Institute have developed a new technique to emboss the structures of shark skin into aircraft paints.

The idea is to make surfaces more aerodynamic and reduce fuel consumption by about one percent and lower operating costs.

The trials on Lufthansa jets represent the last phase before possible industrial application, said Denis Darracq, head of research and flight physics technology at Airbus.

"The expected results have been achieved in terms of performance. It's now a matter of measuring operational efficiency and durability," Darracq said.

"An airline must not have to clean its aircraft after every flight. The paint needs to last for several years," he said.

The engineer estimated that if an aircraft was covered by between 40-70 percent in the new paint, it can cut fuel consumption by around one percent for very little outlay.

And with high fuel prices and customers becoming increasingly sensitive to the environmental impact of flying, that would represent an "enormous benefit" for an airline, Darracq argued.

Nature is also the inspiration for another state-of-the-art technology that is already being used by the industry and may have wider applications.

The leaf of the lotus plant has a unique microstructure consisting of tiny bumps topped with tiny hairs that make the leaf highly water repellent.

Special surface coatings have been developed to mimic this effect and they are already used in the interior of the A380 to make it easier to clean.

But Airbus is also looking into whether such coatings can be used on the exterior of aircraft as well.

"De-icing is a real problem for planes and represents a substantial cost factor. If there were surfaces where water cannot collect, they wouldn't freeze over and that would represent a big step forward," said Darracq.

Airlines' growing interest could therefore help accelerate research in surface technologies "and these may be ready for industrial application in a number of years," the engineer said.

- AFP



Read More..

Internet rules: More cats. LESS CAPS




















Our 12 Rules of the Internet


Our 12 Rules of the Internet


Our 12 Rules of the Internet


Our 12 Rules of the Internet


Our 12 Rules of the Internet


Our 12 Rules of the Internet


Our 12 Rules of the Internet


Our 12 Rules of the Internet


Our 12 Rules of the Internet


Our 12 Rules of the Internet


Our 12 Rules of the Internet


Our 12 Rules of the Internet


Our 12 Rules of the Internet





<<


<





1




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13



>


>>







STORY HIGHLIGHTS


  • Yes, there ARE some rules to the Internet, though, for now they're mainly an inside joke

  • Some rules based on pop culture, some have become Web memes

  • Other rules ominously quote Anonymous

  • Is there a need for rules on the vast and wild Web? Depends on where you stand




Editor's note: In the gallery above, we've selected a handful of our favorite Internet rules, or truths. (You might recognize a few.) What are some of yours? Tell us in the comments. We'll feature some of the best on CNN.


(CNN) -- Hello!


Welcome to the Internet. It's a big place, so let me show you around.


You're approaching Oversharing Pass, where residents routinely post too much information. The Facebook Gorge and Twitter Triangle are particularly nefarious time-sucks. Restraint is advised.


Up ahead is Hyperbole Junction, which is the Worst. Spot. Ever. We recommend that you maintain an even keel and stay to the center; the extreme left and right can be dangerous.


And over there is the infamous Lair of Sociopaths, the home of trolls and loners who mercilessly mock everyone who enters their territory. Watch your step: They may trip you up and you'll fall into the Chasm of Lulz.


Our world isn't all dangerous, of course. You may visit Squee City, where images of cute cats and laughing babies fill the landscape. You'll also meet countless kind strangers, hilarious raconteurs and hard-working fact-checkers. They make it all worthwhile.


Hmm. Maybe it would be easier if you had a guide -- you know, some rules to help you find your way.


What, you didn't know there are rules of the Internet?


Of course there are rules. How do you think we maintain order around here?


A parody of rules


That's a joke.


But there really are some rules of the Internet -- even if they, too, began as kind of a joke.


According to the site KnowYourMeme.com, the Rules began around 2006 as a guide for the Internet collective Anonymous and emerged on the old Encyclopedia Dramatica, a bawdy meme catalog. Soon a version emerged on 4chan, an online bulletin board where most users post anonymously, says Jamie Cohen, director of web/digital media at Hofstra University's School of Communication.


"Chris Poole (4chan's founder) kind of designed it, kind of like a Netiquette rules," he says, describing the unspoken code of conduct that lubricates Internet discourse. (Poole has attributed the rules to Gaia Online, a role-playing community.)


But the rules of the Internet deliberately mocked many of those conventions. The self-reflexive parody fit perfectly with its community's attitude, points out Anthony Rotolo, a professor at Syracuse University's School of Information Studies.


"These jokes are meant to comment on something happening in the world," he says. "Later they get accepted as truisms or become a meme."


The absurdity has been reflected even in the supposed number of rules. Though the best-known first version claimed there were 50 rules, only 18 were listed. Number 1 was initially "Do not talk about Rules 2-33"; no Rules 2-33 were on the list.


The sarcastic attitude was reinforced by the kicker found on Encyclopedia Dramatica. It was a parody of Wikipedia's stub language: "This article is crap. You can help by completely re-writing it."


'Fight Club' and Monty Python


Very quickly, the lists started multiplying and expanding, liberally borrowing from comedy, Web culture and math-science tropes. On one list, a few were designated by complex numbers and mathematical symbols. Some were observations; others were directives.




Some have traced the Internet rules to Chris Poole, the founder of 4chan.



Two rules were taken from "Fight Club": "You do not talk about 4chan (or "/b/," 4chan's random, free-wheeling bulletin board) and "You DO NOT talk about 4chan." One version of Rule 6 stated "There is no Rule 6," which is from a Monty Python sketch. Rule 42, "Always bring a towel," was drawn from Douglas Adams' "The Hitchhiker's Guide to the Galaxy" series. (If you have to ask, read the books.) "Profit," Rule 49, came from "South Park."


Other rules went the reverse direction and became part of mainstream culture. Rule 34 -- "If it exists, there is porn of it" -- is likely the most famous. But there's also "Pics or it didn't happen" (Rule 30), "For every given male character, there is a female version of that character; conversely for every given female character, there is a male version of that character" (Rule 63) and, of course, the corollary to Rule 34 -- "If no porn of it exists at the moment, it will be made" (Rule 35).


Most retained a sense of humor, riffing off established rules and occasionally ending with a giggly "No exceptions."


But a handful were, and remain, as serious as a judge -- notably the three directly about Anonymous (commonly Rules 3-5):


- We are Anonymous.


- We are legion.


- We do not forgive, we do not forget.


The overall Internet rules may have started as a joke, but such ominous language from Anonymous speaks to some of the paradoxes of the Web:


Rules? Why do we need some stinkin' rules?


After all, rules can be helpful -- or divisive. They can create community -- or subvert it.


Even Anonymous, the activist group itself, cuts both ways, says Rotolo. When it hacked the extremist Westboro Baptist Church, many people cheered. But when it goes after less unpopular targets, some cry vigilantism.


Cohen says that the rules themselves try to have it both ways. They're funny until someone gets hurt.


They "play more of a game type of role. They can be bent or broken or cheated or moved around, as you would in any game that has no physical reaction," he says. "That doesn't take into account ever the result of real people being affected by this -- such as teenagers, children, anybody who's seeing things that they shouldn't."


He adds, "There's a lot of rules in there that work for (the creators) more than anyone else. Until they become victims of their own thing, they don't know how powerful the rules are."


Evolving from the Wild West


Of course, the Internet isn't that old, and we're still in its Wild West era in many ways. As the technology evolves from a handful of hackers on Usenet bulletin boards to billions of users on officially sponsored sites, the customs -- the rules -- of the Web will evolve with it.


But we're not talking about the kinds of changes that your family makes to the rules of Monopoly (no, Free Parking is NOT for the pool of money acquired via Chance and Community Chest). We're talking something more expansive: All the established customs of our carbon-based life forms, making way for the instantaneous and virtual modes of silicon-based electronics.


Who knows what new rules may be written?


"When you're in the midst of social change, it's impossible to determine where it's going," says Peter S. Vogel, a former programmer who's now a Dallas-based attorney. "And I think we are in the greatest social change in the history of humans, because there are no boundaries of geography or time."


We haven't even sorted out what happens when the differences in local culture meet global technology. Bruce Umbaugh, a philosophy professor at Webster University in St. Louis who teaches a course on philosophy and technology, argues that not all parts of the world are as tolerant or open-minded as Western democracies.



There's a lot of rules in there that work for (the creators) more than anyone else.
Jamie Cohen, Hofstra University



"There are a lot of other places in the world that are actively using the technology of the Internet to control the free communication among citizens, and to identify critics of the government and hurt them," he says. "We need to be mindful in what we advocate from our perspective that the tools that are implemented on the Net are tools for the global Net."


In other words, citizens of other countries already face actual, enforceable rules -- unlike the folkways established by Web users in the West. Witness the frictions of the Arab Spring, or the restrictions of societies such as North Korea.


It's the kind of perspective that provides a different context for the issues raised by a libertarian, anything-goes Internet. It's hard enough to stop "Star Wars" comment boards from devolving into flamebaiting, meme-generating files of NSFW Yodas.


So for now, we're still making our way through the Series of Tubes, and nobody knows where the boundaries lie. We joke, we grimace and we marvel at the creativity of the hive mind. The Internet is a big place, and countless cultures have set up residence. Eventually, what is now humor may lose its zing; what are now customs may become laws.


Will the rules ever become The Rules? Maybe some future generation will figure out the true guideposts of Internet life, and the singularity will be upon us.


Nah. It'll never happen.


What did we miss? Share your rules for the internet below in the comments. We'll feature some of the best on CNN.







Read More..

After dramatic meteor strike, Russians pick up pieces

CHELYABINSK, Russia A small army of workers set to work Saturday to replace acres of windows shattered by the enormous explosion from a meteor, while other residents contemplated the astonishing event with pride and humor.

The fireball that streaked into the sky over Chelyabinsk at about sunrise Friday was undeniably traumatic. Nearly 1,200 people were reported injured by the shock wave from the explosion, estimated to be as strong as 20 Hiroshima atomic bombs.

But it also brought a sense of cooperation and humor to a tough industrial city in a troubled region. Large numbers of volunteers came forward to help fix the damage caused by the explosion and many residents came together on the Internet — first to find out what happened and soon to make jokes about it.

One of the most popular jests: Residents of the meteor were terrified to see Chelyabinsk approaching.




Play Video


Meteorites fall from the sky in Russia



Chelyabinsk, nicknamed Tankograd because it produced the famed Soviet T-34 tanks, can be as grim as its backbone heavy industries. Long winters where temperatures routinely hit minus-30 Celsius (minus-4 Fahrenheit) add to a general dour mien, as do worries about dangerous facilities in the surrounding region.

In 1957, a waste tank at the Mayak nuclear weapons plant in the Chelyabinsk region exploded, contaminating 9,200 square miles and prompting authorities to evacuate 10,000 nearby residents. It is now Russia's main nuclear waste disposal facility. A vast plant for disposing of chemical weapons lies 50 miles east of the city.

"The city is a place where people always seem bitter with each other," said music teacher Ilya Shibanov. But the meteor "was one of the rare times when people started to live together through one event."

"For most people, it's a good excuse for a joke," he said.

It was also a reason for Shibanov to quickly concoct a rap video that got wide Internet attention, including the lines: ""Pow, pow, pow — everything flew and factory windows crumbled. This Friday the bars are going to be full, so be ready for the aftermath."




Play Video


Why did meteor do so much damage?



But for many, it's been a reason to roll up their sleeves and get to work repairing the more than 4,000 buildings in the city and region where windows were shattered, or to provide other services.

More than 24,000 people, including volunteers, have mobilized in the region to cover windows, gather warm clothes and food, and make other relief efforts, the regional governor's office said. Crews from glass companies in adjacent regions were being flown in.

Gov. Mikhail Yurevich on Saturday said that damage from the high-altitude explosion -believed to have been as powerful as 20 Hiroshima bombs — is estimated at 1 billion rubles ($33 million). He promised to have all the broken windows replaced within a week.

But that is a long wait in a frigid region. The midday temperature in Chelyabinsk was 10 F, and for many the immediate task was to put up plastic sheeting and boards on shattered residential windows.

Meanwhile, the search continued for major fragments of the meteor.




Play Video


Scientist: "Mother Nature has shown Hollywood who's boss"



In the town of Chebarkul, 50 miles west of Chelyabinsk city, divers explored the bottom of an ice-crusted lake looking for meteor fragments believed to have fallen there, leaving a 20-foot-wide hole. Emergency Ministry spokeswoman Irina Rossius told Russian news agencies the search hadn't found anything.

Police kept a small crowd of curious onlookers from venturing out onto the icy lake, where a tent was set up for the divers.

Many of them were still trying to process the memories of the strange day they'd lived through.

Valery Fomichov said he had been out for a run when the meteor streaked across the sky shortly after sunrise.

"I glanced up and saw a glowing dot in the west. And it got bigger and bigger, like a soccer ball, until it became blindingly white and I turned away," he said.

In a local church, clergyman Sexton Sergei sought to derive a larger lesson.

"Perhaps God was giving a kind of sign, so that people don't simply think about their own trifles on earth, but rather look to the heavens once in a while."

In Chelyabinsk, university student Ksenia Arslanova said she was pleased that people in the city of 1 million generally behaved well after the bewildering flash and explosions.




10 Photos


Meteorites crash into Russia



"People were kind of ironic about it. And that's a good thing, that people didn't run to the grocery store. Everyone was calm," the 19-year-old architecture student said. "I'm proud that our city didn't fall into depression."

Chelyabinsk residents weren't the only ones watching the skies, however.

Stargazers in the San Francisco Bay Area caught a glimpse of an apparent meteor shower Friday night. Social media users reported seeing the blue flash flying west around 8 p.m. and sightings were reported throughout the Bay Area, reports CBS San Francisco.

Based on reports, Jonathan Braidman, an astronomer with the Chabot Space and Science Center in Oakland, said that it seems Friday night's fireball was what astronomers call a "sporadic meteor," an event that can happen several times a day but most of the time happens over the ocean, away from human eyes, and brings as much as 15,000 tons of space debris to Earth each year.

Meteors, hunks of rock and metal from space that fall to Earth, burn up as they go through Earth's atmosphere, which is what apparently caused Friday night's bright flash of light, Braidman said.

It was likely smaller than another meteor that landed in the Bay Area in October, which caused a loud sonic boom as it fell, breaking apart and spreading rocks, called meteorites, in the North Bay.

And Cuba apparently experienced a phenomenon similar to the meteorite that detonated over Russia this week, island media reported, with startled residents describing a bright light in the sky and a loud explosion that shook windows and walls.

There were no reports of any injuries or damage such as those caused by the Russia meteorite. In a video from a state TV newscast posted on the website CubaSi late Friday, unidentified residents of the central city of Rodas, near Cienfuegos, said the explosion was impressive.

"On Tuesday we left home to fish around five in the afternoon, and around 8:00 we saw a light in the heavens and then a big ball of fire, bigger than the sun," one local man said in the video.

"My home shook completely," said a woman. "I had never heard such a strange thing."

Marcos Rodriguez, whom the video identified as a specialist in anthropology, said all signs point to a meteorite.

A reporter said a similar phenomenon was observed in 1994 elsewhere in Cienfuegos province.




Play Video


Watch: Asteroid's close encounter with Earth



The video said Cuban authorities were looking for any fragments that may have fallen to the earth.

Friday's meteorite strike came shortly before Asteroid 2012 DA14 made the closest recorded pass of an asteroid to the Earth -- about 17,150 miles. But the European Space Agency in a tweet said its experts had determined there was no connection -- just cosmic coincidence. The asteroid passed Earth without incident at approximately 2:30 pm EST Friday.

Read More..

Meteor Blast 'Something We Only Saw in Movies'












A day after a massive meteor exploded over this city in central Russia, a monumental cleanup effort is under way.


Authorities have deployed around 24,000 troops and emergencies responders to help in the effort.


Officials say more than a million square feet of windows -- the size of about 20 football fields -- were shattered by the shockwave from the meteor's blast. Around 4,000 buildings in the area were damaged.


The injury toll climbed steadily on Friday. Authorities said today it now stands at more than 1,200. Most of those injuries were from broken glass, and only a few hundred required hospitalization.


According to NASA, this was the biggest meteor to hit Earth in more than a century. Preliminary figures suggest it was 50 feet wide and weighed more than the Eiffel Tower.










SEE PHOTOS: Meteorite Crashes in Russia


NASA scientists have also estimated the force of the blast that occurred when the meteor fractured upon entering Earth's atmosphere was approximately 470 kilotons -- the equivalent of about 30 Hiroshima bombs.


Residents said today they still can't believe it happened here.


"It was something we only saw in the movies," one university student said. "We never thought we would see it ourselves."


Throughout the city, the streets are littered with broken glass. Local officials have announced an ambitious pledge to replace all the broken windows within a week. In the early morning hours, however, workers could still be heard drilling new windows into place.


Authorities have sent divers into a frozen lake outside the city, where a large chunk of the meteor is believed to have landed, creating a large hole in the ice. By the end of the day they had not found anything.


They are not the only ones looking for it.


Meteor hunters from around the world are salivating at what some are calling the opportunity of a lifetime. A small piece of the meteor could fetch thousands of dollars and larger chunks could bring in even hundreds of thousands.



Read More..

False memories prime immune system for future attacks









































IN A police line-up, a falsely remembered face is a big problem. But for the body's police force – the immune system – false memories could be a crucial weapon.












When a new bacterium or virus invades the body, the immune system mounts an attack by sending in white blood cells called T-cells that are tailored to the molecular structure of that invader. Defeating the infection can take several weeks. However, once victorious, some T-cells stick around, turning into memory cells that remember the invader, reducing the time taken to kill it the next time it turns up.












Conventional thinking has it that memory cells for a particular microbe only form in response to an infection. "The dogma is that you need to be exposed," says Mark Davis of Stanford University in California, but now he and his colleagues have shown that this is not always the case.












The team took 26 samples from the Stanford Blood Center. All 26 people had been screened for diseases and had never been infected with HIV, herpes simplex virus or cytomegalovirus. Despite this, Davis's team found that all the samples contained T-cells tailored to these viruses, and an average of 50 per cent of these cells were memory cells.












The idea that T-cells don't need to be exposed to the pathogen "is paradigm shifting," says Philip Ashton-Rickardt of Imperial College London, who was not involved in the study. "Not only do they have capacity to remember, they seem to have seen a virus when they haven't."












So how are these false memories created? To a T-cell, each virus is "just a collection of peptides", says Davis. And so different microbes could have structures that are similar enough to confuse the T-cells.












To test this idea, the researchers vaccinated two people with an H1N1 strain of influenza and found that this also stimulated the T-cells to react to two bacteria with a similar peptide structure. Exposing the samples from the blood bank to peptide sequences from certain gut and soil bacteria and a species of ocean algae resulted in an immune response to HIV (Immunology, doi.org/kgg).












The finding could explain why vaccinating children against measles seems to improve mortality rates from other diseases. It also raises the possibility of creating a database of cross-reactive microbes to find new vaccination strategies. "We need to start exploring case by case," says Davis.












"You could find innocuous pathogens that are good at vaccinating against nasty ones," says Ashton-Rickardt. The idea of cross-reactivity is as old as immunology, he says. But he is excited about the potential for finding unexpected correlations. "Who could have predicted that HIV was related to an ocean algae?" he says. "No one's going to make that up!"












This article appeared in print under the headline "False memories prime our defences"




















































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Read More..

US cruise ship passengers' parting gift: bathrobes






WASHINGTON: The 4,000-plus exhausted passengers who lived a hellish four-day ordeal aboard the powerless and drifting Carnival Triumph cruise ship won't be left completely empty handed.

The cruise company is making a gift to the travelers of the bathrobes they were using on the ship, the company announced Friday.

"Of course the bathrobes for the Carnival Triumph are complimentary," it said in a tweet on the official @carnivalcruise account.

But the announcement has been received with less than full-throated cheers.

"Who wants a stinky robe?!" tweeted a reporter in North Carolina, Astrid Martinez, while another user of the social media site, Natalie Eshaya, enthused sarcastically, "Oh how generous."

Another skeptic, Paul Nather, wondered "What do you think the going rate for a Carnival cruise bathrobe will be on eBay tomorrow?"

The white bathrobe has become an unlikely symbol of the nightmare of the cruise-goers, who donned them to attract attention as they stood on the drifting ship.

Others used the white terrycloth as a canvas to write messages, with one passenger proclaiming, "I survived Carnival's triumph redbags" -- a reference to the bags that substituted for toilets.

The Triumph docked Friday morning in the port of Mobile, Alabama. It had originally been scheduled to return to port early Monday after a weekend stop in Cozumel in Mexico, before an engine room blaze left the massive vessel without electricity to power the kitchens, toilets, and other necessities.

- AFP/ck



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Sen. Rubio drowning in 'water-gate'





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Facebook says it was hacked last month

Social media company Facebook announced Friday that it was hacked last month, which has led to an ongoing investigation.

Below is a statement issued by Facebook:

Last month, Facebook Security discovered that our systems had been targeted in a sophisticated attack. This attack occurred when a handful of employees visited a mobile developer website that was compromised. The compromised website hosted an exploit which then allowed malware to be installed on these employee laptops. The laptops were fully-patched and running up-to-date anti-virus software. As soon as we discovered the presence of the malware, we remediated all infected machines, informed law enforcement, and began a significant investigation that continues to this day. We have no evidence that Facebook user data was compromised in this attack.

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This article originally appeared on CNET.

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